Homocysteine and Parkinson’s Disease: A Complex Relationship
نویسنده
چکیده
Abbreviations: ALS: Amyotrophic Lateral Sclerosis; ATP: Adenosine Triphosphate; CBS: Cystathionine β-Synthase; CNS: Central Nervous System; COMT: Catechol-O-Methyl-Transferase; CYP2E1: Cytochrome P450 2E1; eNOS: Endothelial Nitric Oxide Synthase; Hcy: Homocysteine; L-DOPA: Levodopa; mPT: Mitochondrial Permeability Transition; MPTP: 1-Methyl 4-Phenyl 1,2,3,6-Tetrahydropyridine; MTHFR: Methylene Tetrahydrofolate Reductase; NMDA: N-methyl-D-Aspartate; NO: Nitric Oxide; 6-OHDA: 6-Hydroxydopamine; PD: Parkinson’s Disease; PON1: Paraoxonase 1; ROS: Reactive Oxygen Species; SAH: S-Adenosyl-Hcy; SAM: S-Adenosyl Methionine; UPDRS: Unified Parkinson’s Disease Rating Scale; VNTR: Variable Number Tandem Repeat
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